Overview:The Immune System and the Developing Brain - Colloquium Series on the Developing Brain - The developing brain is exquisitely sensitive to both endogenous and exogenous signals which direct or significantly alter the developmental trajectory of cells, neural circuits, and associated behavioral outcomes for the life of the individual. Contrary to initial dogma that the brain is one of the few organs within the body that is immune-privileged, evidence indicates that the immune system has a critical role in brain function during development as well as during sickness and health in adulthood. Microglia are the primary immune cells within the brain, and they are in constant communication with the peripheral immune system and surrounding cell types within the brain. We describe the important role of the immune system, including microglia, during brain development, and discuss some of the many ways in which immune activation during early brain development can affect the later-life outcomes of neural function, immune function, and cognition. Growing evidence indicates that there is a strong link between many neuropsychiatric disorders and immune dysfunction, with a distinct etiology in neurodevelopment. Thus, understanding the role of the immune system and immune activation during the critical period of brain development is a necessary step toward understanding the potential origins of these devastating disorders.
This book is on page /0fb06c92acf561788291222b8bb2eff7/book/1603729720-9781615043514. It was written by the following authors: Staci D. Bilbo, Jaclyn Schwarz. Book The Immune System and the Developing Brain - Colloquium Series on the Developing Brain, which can be read online, published by the company: Morgan & Claypool Publishers. Other books on similar topics can be found in sections: Medicine, Science, Technology. The book was published on 2010-12-30. It has 128 pages and is published in Paperback format and weight 238 g. File for download The Immune System and the Developing Brain - Colloquium Series on the Developing Brain has PDF format and is called the-immune-system-and-the-developing-brain-colloquium-series-on-the-developing-brain.pdf. Other books you can download below. Our poumm.fr site is not responsible for the content of PDF files.
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